|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||2 µg/ml|
|Western Blot (WB)||See 3 publications below|
|Immunohistochemistry (IHC)||See 3 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Rat , Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||Recombinant tyrosinase protein.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Albino locus protein; CMM8; LB24-AB; Monophenol monooxygenase; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; Tumor rejection antigen AB; Tyrosinase
Gene Aliases: albino; ATN; c; CMM8; OCA1; OCA1A; OCAIA; SHEP3; skc35; TYR
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.