|Immunocytochemistry (ICC)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
|Immunohistochemistry (IHC)||See 12 publications below|
|ELISA (ELISA)||See 1 publications below|
|Western Blot (WB)||See 3 publications below|
|Immunocytochemistry (ICC)||See 3 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
|Tested Species reactivity||Dog, Cat, Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant tyrosinase protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-14174 targets Tyrosinase in ICC, IF, IHC (P), and WB applications and shows reactivity with Canine, Feline, and Human samples.
The MA5-14174 immunogen is recombinant tyrosinase protein.
Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LB24-AB; Monophenol monooxygenase; oculocutaneous albinism IA; SK29-AB; Tumor rejection antigen AB; Tyrosinase; tyrosinase (oculocutaneous albinism IA)
Gene Aliases: ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3; TYR
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.