|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 194 of Human UBC3B|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31003 targets UBC3B in WB applications and shows reactivity with Human and mouse samples.
The PA5-31003 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 194 of Human UBC3B.
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC34B; E2 ubiquitin-conjugating enzyme R2; E2-CDC34B; UBC3B; Ubiquitin carrier protein R2; ubiquitin conjugating enzyme E2R 2; Ubiquitin-conjugating enzyme E2 R2; Ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; ubiquitin-conjugating enzyme UBC3B; Ubiquitin-protein ligase R2
Gene Aliases: 1200003M11Rik; CDC34B; E2-CDC34B; UBC3B; UBE2R2
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