|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 102 of Human UBE2A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27186 targets UBE2A in WB applications and shows reactivity with Human samples.
The PA5-27186 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 102 of Human UBE2A.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Protein Aliases: E2 ubiquitin-conjugating enzyme A; HHR6A; HR6A; MRXS30; MRXSN; RAD6 homolog A; RAD6A; UBC2; Ubiquitin carrier protein A; ubiquitin conjugating enzyme E2A; Ubiquitin-conjugating enzyme E2 A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); Ubiquitin-protein ligase A
Gene Aliases: HHR6A; MRXS30; MRXSN; RAD6A; UBC2; UBE2A
UniProt ID: (Human) P49459
Entrez Gene ID: (Human) 7319