|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 207 of Human UBE2E3|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31122 targets UBE2E3 in WB applications and shows reactivity with mouse samples.
The PA5-31122 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 207 of Human UBE2E3.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E2 ubiquitin-conjugating enzyme E3; UBCH9; UbcM2; Ubiquitin carrier protein E3; ubiquitin-conjugating enzyme 4; Ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog; ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog; Ubiquitin-protein ligase E3; yeast)
Gene Aliases: Ubce4; Ubcm2; Ube2e3
UniProt ID: (Mouse) P52483
Entrez Gene ID: (Mouse) 22193
Molecular Function: ligase
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.