|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 413 and 715 of Human UBE4A|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29197 targets UBE4A in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29197 immunogen is recombinant fragment corresponding to a region within amino acids 413 and 715 of Human UBE4A.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E4; RING-type E3 ubiquitin transferase E4 A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A (UFD2 homolog; ubiquitination factor E4A (UFD2 homolog, yeast); UBOX2; UFD2; yeast)
Gene Aliases: E4; KIAA0126; UBE4A; UBOX2; UFD2
UniProt ID: (Human) Q14139
Entrez Gene ID: (Human) 9354
Molecular Function: enzyme modulator
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