|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 113 and 309 of Human UPRT|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31684 targets UPRT in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31684 immunogen is recombinant fragment corresponding to a region within amino acids 113 and 309 of Human UPRT.
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FUR1; RP11-311P8.3; UMP pyrophosphorylase; UPP; UPRTase; uracil phosphoribosyltransferase (FUR1) homolog; Uracil phosphoribosyltransferase homolog
Gene Aliases: FUR1; Gm774; UPP; UPRT
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