|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 272 of Human VAM1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31064 targets VAM1 in WB applications and shows reactivity with Human samples.
The PA5-31064 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 272 of Human VAM1.
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAGUK p55 subfamily member 6; MAGUK protein p55T; membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); p55T; PALS2; protein associated with Lin7 2; VAM-1; VAM1; VELI-associated MAGUK 1
Gene Aliases: MPP6; p55T; PALS2; VAM-1; VAM1
UniProt ID: (Human) Q9NZW5
Entrez Gene ID: (Human) 51678
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