|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (DESEDPGKDLDH) corresponding to the C-terminus amino acids of USO1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: General vesicular transport factor p115; P115; Protein USO1 homolog; TAP; transcytosis associated protein; Transcytosis-associated protein; USO1; USO1 homolog, vesicle docking protein; USO1 homolog, vesicle docking protein (yeast); USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein; vesicle docking protein p115; Vesicle-docking protein
Gene Aliases: P115; TAP; USO1; VDP
UniProt ID: (Human) O60763
Entrez Gene ID: (Human) 8615
Molecular Function: membrane traffic protein
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