|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 36 and 177 of Human VDP/p115|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30281 targets VDP/p115 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-30281 immunogen is recombinant protein fragment corresponding to a region within amino acids 36 and 177 of Human VDP/p115.
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: General vesicular transport factor p115; P115; Protein USO1 homolog; TAP; transcytosis associated protein; transcytosis associated protein p115; Transcytosis-associated protein; USO1 homolog; USO1 homolog, vesicle docking protein; USO1 vesicle docking protein homolog; VDP; vesicle docking protein; vesicle docking protein p115; vesicle docking protein, 115 kDa; Vesicle-docking protein
Gene Aliases: 115kDa; P115; TAP; USO1; VDP
Molecular Function: membrane traffic protein
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