|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||1:500|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Clone||KDR-2 or 260.4|
|Immunogen||Recombinant, extracellular fragment of human VEGF2.|
|Contains||15mM sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-24888 detects VEGF Receptor 2 from human samples.
MA1-24888 has been successfully used in immunohistochemistry, ELISA and Western blot procedures. The predicted molecular weight is 152 kDa.
The MA1-24888 immunogen is recombinant, extracellular fragment of human VEGF2.
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 6130401C07; CD309; Fetal liver kinase 1; fetal liver kinase-1; FLK-1; Flk1; KDR; Kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); Krd-1; Ly73; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR-2; VEGFR2
Gene Aliases: CD309; FLK1; KDR; VEGFR; VEGFR2
UniProt ID: (Human) P35968
Entrez Gene ID: (Human) 3791
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