|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human VEGF1|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-13297 targets Vascular Growth Factor (VEGF) in IF and WB applications and shows reactivity with Human samples.
The PA5-13297 immunogen is a synthetic peptide between 66-95 amino acids from the N-terminal region of Human VEGF.
VEGF1 is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF1 have been associated with proliferative and nonproliferative diabetic retinopathy.
Protein Aliases: Vascular endothelial growth factor A; Vascular endothelial growth factor A [Precursor]; vascular endothelial growth factor A121; vascular endothelial growth factor A165; Vascular permeability factor; VEGF; VEGF-A; VEGF1; VEGFA; VPF
Gene Aliases: MVCD1; VEGF; VEGFA; VPF
UniProt ID: (Human) P15692
Entrez Gene ID: (Human) 7422