|Flow Cytometry (Flow)||1:10-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 263-291 amino acids from the central region of human VPS26A|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, C. elegans, mouse, rat and Xenopus and zebrafish based on sequence homology.
VPS26A is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hVPS26; vacuolar protein sorting 26 homolog A; Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; VPS26; VPS26 retromer complex comonent A; VPS26 retromer complex component A; VPS26A
Gene Aliases: HB58; Hbeta58; PEP8A; VPS26; VPS26A
UniProt ID: (Human) O75436
Entrez Gene ID: (Human) 9559
Molecular Function: membrane traffic protein
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