|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 226 and 461 of Human VPS41|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31363 targets VPS41 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31363 immunogen is recombinant fragment corresponding to a region within amino acids 226 and 461 of Human VPS41.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.
Protein Aliases: HVPS41; hVps41p; HVSP41; S53; vacuolar assembly protein 41; vacuolar protein sorting 41 homolog; Vacuolar protein sorting-associated protein 41 homolog; VPS41 HOPS complex subunit
Gene Aliases: HVPS41; hVps41p; HVSP41; VPS41
UniProt ID: (Human) P49754
Entrez Gene ID: (Human) 27072