|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ESSQVTSRSASRR) corresponding to the C-terminus amino acids of VPS45|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and mouse based on sequence homology.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: h-VPS45; H1; H1VPS45; hlVps45; leucocyte vacuolar protein sorting 45; RP11-458I7.2; vacuolar protein sorting 45 homolog (S. cerevisiae); vacuolar protein sorting 45A; vacuolar protein sorting 45A (yeast homolog); vacuolar protein sorting 45A (yeast); vacuolar protein sorting 45B (yeast); vacuolar protein sorting protein similar to S. cerevisiae Vsp45p; Vacuolar protein sorting-associated protein 45; VPS45; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
Gene Aliases: H1; H1VPS45; SCN5; VPS45; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
UniProt ID: (Human) Q9NRW7
Entrez Gene ID: (Human) 11311
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