|Tested Species reactivity||Human, Rat|
|Host / Isotype||Guinea pig / IgG|
|Immunogen||Peptide corresponding to residues YTGSLKPEDAEVFKDSMVPGEK of the carboxy-terminus of rat VR1|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-29770 detects VR1 from human and rat samples.
PA1-29770 has been successfully used in immunohistochemistry applications.
The PA1-29770 immunogen is YTGSLKPEDAEVFKDSMVPGEK Corresponding to residues of the carboxy-terminus of rat VR1.
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Capsaicin receptor; DKFZp434K0220; Osm-9-like TRP channel 1; OTRPC1; Transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel, subfamily V, member 1; transient receptor potential vanilloid 1 supraoptic nucleus; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b; TrpV1; Vanilloid receptor 1; vanilloid receptor subtype 1; vanilloid receptor type 1 like protein 1; Vanilloid receptor type 1-like; vanilloid type 1 receptor; VR1
Gene Aliases: TRPV1; TRPV1_SON; VR.5'sv; VR1; Vr1l; Vr1l1
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