|Western Blot (WB)||1:1000|
|Immunohistochemistry (IHC)||See 1 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Rat|
|Published species reactivity||Rat Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminal region of rat SLC32A1 conjugated to KLH|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and non-human primate based on 100% sequence homology.
In Western blot, this antibody is specific for the ~53 kDa VGAT protein.
The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GABA and glycine transporter; GVAT; rGVAT; Solute carrier family 32 member 1; Vesicular GABA transporter; Vesicular GABA transporterr; Vesicular inhibitory amino acid transporter
Gene Aliases: Slc32a1; Vgat; Viaat
UniProt ID: (Rat) O35458
Entrez Gene ID: (Rat) 83612
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