|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 403 and 665 of Human WHIP|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28532 targets WHIP in WB applications and shows reactivity with Human samples.
The PA5-28532 immunogen is recombinant fragment corresponding to a region within amino acids 403 and 665 of Human WHIP.
Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase WRNIP1; bA420G6.2; putative helicase RUVBL; RP11-420G6.2; Werner helicase-interacting protein 1; WHIP; WRNIP1
Gene Aliases: bA420G6.2; WHIP; WRNIP1
UniProt ID: (Human) Q96S55
Entrez Gene ID: (Human) 56897
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.