|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 289 of Human WIG1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28552 targets WIG1 in IF, IHC (P), and WB applications and shows reactivity with Human and Mouse samples.
The PA5-28552 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 289 of Human WIG1.
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
Protein Aliases: matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein; PAG608; WIG-1; WIG-1/PAG608 protein; WIG1; wild-type p53-induced gene 1 protein; zinc finger; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; zinc finger protein WIG1; zmat3
Gene Aliases: PAG608; WIG-1; WIG1; ZMAT3
UniProt ID: (Human) Q9HA38