|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human WNT10B expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15557 targets WNT10B in IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15557 immunogen is purified recombinant fragment of human WNT10B expressed in E. Coli.
MA5-15557 detects WNT10B which has a predicted molecular weight of approximately 43kDa.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
Protein Aliases: Protein Wnt-10b; Protein Wnt-12; SHFM6; wingless-type MMTV integration site family member 10B; wingless-type MMTV integration site family, member 10B; WNT-10B protein; WNT-12; WNT10B
Gene Aliases: SHFM6; WNT-12; WNT10B; WNT12
UniProt ID: (Human) O00744
Entrez Gene ID: (Human) 7480
Molecular Function: signaling molecule