|Western Blot (WB)||1:500-1:5000|
|Tested Species reactivity||Human|
|Host / Isotype||Chicken / IgY|
|Immunogen||Purified recombinant WRB corresponding to the chromosome 21 gene (Human).|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-9557 detects WRB in human samples.
PA1-9557 has been successfully used in Western blot procedures. By Western blot, PA1-9557 detects a 16 kDa protein representing WRB.
PA1-9557 immunogen is a purified recombinant WRB corresponding to the chromosome 21 gene (Human).
Store at 4C for up to 1 week. Store at -20C long term.
This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CHD5; Congenital heart disease 5 protein; Tail-anchored protein insertion receptor WRB; Tryptophan-rich basic protein; WRB
Gene Aliases: CHD5; GET1; WRB
UniProt ID: (Human) O00258
Entrez Gene ID: (Human) 7485
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