|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:500|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal sequence within the human XAGE-1 protein.|
|Storage buffer||whole serum|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-32314 detects XAGE1 from human samples.
PA1-32314 has been successfully used in immunoprecipitation, Western blot applications.
The PA1-32314 immunogen is: Synthetic peptide made to an internal sequence within the human XAGE-1 protein.
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants.
Protein Aliases: Cancer/testis antigen 12.1; cancer/testis antigen family 12, member 1c; cancer/testis antigen family 12, member 1d; cancer/testis antigen family 12, member 1e; cancer/testis associated protein; CT12.1; CT12.1A; CTP9; G antigen family D member 2; GAGED2; protein XAGE-1; X antigen family member 1; X antigen family, member 1C; X antigen family, member 1D; X antigen family, member 1E; XAGE-1; XAGE1
Gene Aliases: CT12.1; CT12.1C; CT12.1D; CT12.1E; CTP9; GAGED2; XAGE-1; XAGE1; XAGE1A; XAGE1B; XAGE1C; XAGE1D; XAGE1E
UniProt ID: (Human) Q9HD64
Entrez Gene ID: (Human) 653067