|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 294-323 amino acids from the C-terminal region of human YBX2|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
YBX2 is a major constituent of messenger ribonucleoprotein particles (mRNPs). It is nvolved in the regulation of the stability and/or translation of germ cell mRNAs. It binds to Y-box consensus promoter element and to full length mRNA with high affinity in a sequence-independent manner. It binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. YBX2 may mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Contrin; Dbpc; DNA-binding protein C; germ cell specific Y-box binding protein; Germ cell-specific Y-box-binding protein; MSY2 homolog; Y box binding protein 2; Y-box-binding protein 2
Gene Aliases: CONTRIN; CSDA3; DBPC; MSY2; YBX2
UniProt ID: (Human) Q9Y2T7
Entrez Gene ID: (Human) 51087
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