|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
|Western Blot (WB)||1-2 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||GST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254|
|Storage buffer||TBS, pH 7.4|
|Contains||0.05% sodium azide|
|Storage conditions||4° C|
MA5-12624 targets ZAP-70 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-12624 immunogen is gST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254.
Mutations in ZAP-70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP-70 expression also defines a subset of Chronic Lymphocytic Leukaemia (CLL) in patients with unmutated Ig gene and poor clinical course.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; 70kD; Syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase; zeta-chain associated protein kinase, 70kD
Gene Aliases: ADMIO2; IMD48; SRK; STCD; STD; TZK; ZAP-70; ZAP70
UniProt ID: (Human) P43403
Entrez Gene ID: (Human) 7535
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