|Western Blot (WB)||4-7 µg/ml|
|Tested Species reactivity||Bovine, Dog, Chicken, Horse, Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (370 CDRRFANSSDRKKHMH 385) of ZIC2 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects. Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cerebellum zinc finger protein 2; Drosophila); GENA 29; HPE5; kumba; odd-paired homolog; Zic family member 2 (odd-paired homolog; Zic family member 2 (odd-paired homolog, Drosophila); Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2
Gene Aliases: BOS_12680; HPE5; Ku; ZIC2
UniProt ID: (Human) O95409
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.