|Western Blot (WB)||0.25-0.5 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 17 amino acid peptide near the center of human ZIMP7.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is A-20 cell lysate.
PA5-21132 can be used with blocking peptide PEP-1246.
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HRIHFB2007, NET27, TRAFIP20, ZIMP7, hZIMP7; PIAS-like protein Zimp7; Zinc finger MIZ domain-containing protein 2; zinc finger, MIZ-type containing 2
Gene Aliases: D11Bwg0280e; HRIHFB2007; hZIMP7; KIAA1886; NET27; TRAFIP20; ZIMP7; ZMIZ2
Molecular Function: ligase
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