|Immunocytochemistry (ICC)||1: 50-1:150|
|Immunofluorescence (IF)||1: 50-1:150|
|Western Blot (WB)||0.5-1 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide between amino acids 100-175 of the human Crystallin AB protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody is expected to react with rat, ovine, rabbit, monkey, hamster, bovine and porcine based on sequence homology.
Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha (B)-crystallin antibody; Alpha crystallin B chain antibody; Alpha(B)-crystallin; Alpha-crystallin B chain; CryAB antibody; crystallin, alpha B; epididymis secretory protein Li 101; Heat shock protein beta-5; heat-shock 20 kD like-protein; Heat-shock protein beta-5 antibod; HspB5; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component; Rosenthal fiber componet antibody
Gene Aliases: CMD1II; CRYA2; CRYAB; CTPP2; CTRCT16; HEL-S-101; HSPB5; MFM2
UniProt ID: (Human) P02511
Entrez Gene ID: (Human) 1410
Molecular Function: chaperone
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