|Western Blot (WB)||1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide corresponding to residues 335-408 of human beta 2 Adrenergic Receptor.|
|Purification||Antigen affinity chromatography|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-25659 detects beta 2 Adrenergic Receptor from human samples.
PA1-25659 has been successfully used in Western blot procedures.
The PA1-25659 immunogen is a synthetic peptide corresponding to residues 335-408 of human beta 2 Adrenergic Receptor.
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADRB2R; ADRBR; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; B2AR; BAR; Beta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; BETA2AR; catecholamine receptor
Gene Aliases: ADRB2; ADRB2R; ADRBR; B2AR; BAR; BETA2AR
UniProt ID: (Human) P07550
Entrez Gene ID: (Human) 154
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