|Western Blot (WB)||1:500|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Syntehtic peptides corresponding to residues L(260) L E E N (A/P) E K A F Y G S E E(274) of human and mouse beta NAP.|
|Purification||Antigen affinity chromatography|
|Storage buffer||1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-1067 detects beta NAP from human, rat, and mouse samples.
PA1-1067 has been successfully used in Western blot applications. By Western blot this antibody detects a ~119-130 kDa protein representing beta NAP from brain samples.
The PA1-1067 immunogens is a mixture of syntehtic peptides corresponding to residues L(260) L E E N (A/P) E K A F Y G S E E(274) of human and mouse beta NAP. The immunizing peptides (Cat. # PEP-294) are available for purchase for use in neutralization controls.
Beta NAP is closely related to the beta-adaptin and beta-COP coat proteins. Beta NAP is a nonclathrin-associated phosphoprotein expressed exclusively in neurons, from E12 through adulthood. Beta NAP is present in the neurnal soma and nerve terminal as soluble and membrane-bound pools and is associated with a discrete set of nerve-terminal vesicles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adapter-related protein complex 3 beta-2 subunit; adapter-related protein complex 3 subunit beta-2; Adaptor protein complex AP-3 beta-2 subunit; Adaptor protein complex AP-3 subunit beta-2; adaptor related protein complex 3, beta 2 subunit; Adaptor-related protein complex 3 subunit beta-2; adaptor-related protein complex 3, beta 2 subunit; adaptor-related protein complex AP-3, beta 2 subunit; AP-3 complex beta-2 subunit; AP-3 complex subunit beta-2; Beta-3B-adaptin; Beta3B-adaptin; Clathrin a; Clathrin assembly protein complex 3 beta-2 large chain; Neuron-specific vesicle coat protein beta-NAP; Neuronal adaptin-like protein, beta-subunit
Gene Aliases: [b]-NAP; AI549966; AP3B2; AU042881; beta-NAP; beta3B; NAPTB
Molecular Function: membrane traffic protein
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