|Immunocytochemistry (ICC)||1 µg/ml|
|Immunofluorescence (IF)||1 µg/ml|
|Western Blot (WB)||1:500|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 550 - 650 of Human eIF2B epsilon.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA5-19601 targets eIF2B epsilon in IF and WB applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-19601 immunogen is synthetic peptide conjugated to KLH derived from within residues 550 - 650 of Human eIF2B epsilon.
PA5-19601 detects eIF2B epsilon which has a predicted molecular weight of approximately 75 kDa.
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B , a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM, eIF-2B GDP-GTP exchange factor subunit epsilon; eIF-2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; initiation factor eIF-2Be; Translation initiation factor eIF-2B subunit epsilon
Gene Aliases: C81315; CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM
Molecular Function: G-protein modulator RNA binding protein enzyme modulator guanyl-nucleotide exchange factor nucleic acid binding nucleotidyltransferase transferase translation factor translation initiation factor
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