|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Western Blot (WB)||1-2 µg/ml|
|Tested Species reactivity||Hamster|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Colchicine-resistant viable Chinese Hamster Ovary (CHO) cells, followed by purified P170 glycoprotein from CHO cells|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12619 targets p170 in FACS, IF, IHC (F), and WB applications and shows reactivity with Hamster samples.
The MA5-12619 immunogen is colchicine-resistant viable Chinese Hamster Ovary (CHO) cells, followed by purified P170 glycoprotein from CHO cells.
Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.
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