|Western Blot (WB)||1:500 - 1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues Q(13) P P G P E D E D S S L D E S D(28) of human p8.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
PA1-4177 detects human p8 (com1).
PA1-4177 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~9 kDa protein representing Human p8 (com1) in HepGe cell lysates.
The PA1-4177 immunogen is a synthetic peptide corresponding to residues Q(13) P P G P E D E D S S L D E S D(28) of human p8.
The human p8 gene encodes a nuclear protein with strong mitogenic activity, which is expressed in the pancreas in response to acute pancreatitis. Response to TNF alpha and staurosporine-induced apoptosis is not modified by p8 expression. However, cells expressing p8 grow significantly and more rapidly.
Protein Aliases: 60B8AG; CAGA; Candidate of metastasis 1; CGLA; CP-10; L1Ag; MA387; MRP8; NIF; Nuclear protein 1; nuclear protein, transcriptional regulator, 1; Nuclear transcriptional regulator protein 1; P8; Protein p8
Gene Aliases: COM1; NUPR1; P8
UniProt ID: (Human) O60356
Entrez Gene ID: (Human) 26471