|Immunofluorescence (IF)||1 µg/ml|
|Western Blot (WB)||1:1000-1:5000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 700 to the C-terminus of Human p95 NBS1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody is predicted to react with chicken and dog based on sequence homology.
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95, Nijmegen breakage syndrome 1 (nibrin); Cell cycle regulatory protein p95; Nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; p95 protein of the MRE11/RAD50 complex
Gene Aliases: AT-V1; AT-V2; ATV; NBN; NBS; NBS1; P95
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