|Immunofluorescence (IF)||Assay dependent.|
|Immunohistochemistry (Frozen) (IHC (F))||1:10-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:50|
|Western Blot (WB)||Assay dependent.|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Callus cytokeratins isolated from fresh human skin tissue.|
|Storage buffer||tissue culture supernatant with 1% FBS|
|Contains||10mM sodium azide|
|Storage conditions||4° C|
This antibody detects most human keratins.
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 67 kDa cytokeratin; CK-1; cytokeratin 1; Cytokeratin-1; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; Hair alpha protein; HMWCK; K1; keratin 1, type II; Keratin, type II cytoskeletal 1; Keratin-1; KRT1A; NEPPK; pankeratin; Type-II keratin Kb1
Gene Aliases: CK1; EHK; EHK1; EPPK; K1; KRT1; KRT1A; KRTA; NEPPK
UniProt ID: (Human) P04264
Entrez Gene ID: (Human) 3848
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