Custom-Affinity-Ligand-and-Resin-Development
CaptureSelect purification products enable the efficient capture of therapeutic proteins from any feed stream, thereby helping reduce the number of process steps, increase yield, as well as provide a platform approach for purifying any target biotherapeutic.

We offer a unique service for the development of product- and/or process-specific affinity solutions tailored to a target protein and its specific requirements.

The custom ligand can be immobilized on a variety of backbones, including POROS resins, and further developed into an affinity resin, which can be used in large-scale processing of biopharmaceuticals.

Request a technical meeting

Unlock the power of CaptureSelect affinity chromatography, and develop a platform purification process that reduces the number of process steps and helps improve product yield.

Your local sales representative can arrange a technical meeting with our resin development scientists; simply submit a meeting request through the request information button.

Request information

Custom CaptureSelect resin development program
custom-captureSelect-resin-diagram
Start from existing candidates in our pipeline

Through our library development process we have identified a number of candidates that may serve as excellent starting points for a custom affinity resin program. Pipeline opportunities include:

Table 1. CaptureSelect affinity products for purification

Product Stage

Therapeutic Proteins

Viruses

Antibody Types

Research scale purification resins

Antithrombin III (ATIII)
Fibrinogen (Factor I)
Transferrin (TF)
Apolipoprotein H (ApoH)
C1-inhibitor (C1-Inh)
Granulocyte-macrophage colony-stimulating factor (GM-CSF)

Adenovirus (Adv5)

IgA (Fc)
IgA-CH1
IgM
IgE
Bovine IgA
Rabbit IgG (Fc)

Lead Selection

Prothrombin (Factor II)
Deoxyribonuclease (DNAse)

Influenza (HA)

IgG-Fc (mouse)

Prototype resin testing

Universal affinity tag (Uni-Tag)
Factor X

Baculovirus

 

Lead Screening

Interferon alpha and beta (IFNalpha/beta)
Interleukin 2 (hIL2)
Factor V, FXI, FXII, FXIII, and FH
Erythropoietin (EPO)

Exosomes
Lentivirus (VSV-G)

scFv / human VH
IgY

Library Construction

CHO host cell proteins

 

IgG-Fc (rat)

Technical resources and literature

BioProduction resources

Click below to access products brochures, training videos, mobile apps, and more.

Support

 Request more info on BioProduction

For Research Use or Further Manufacturing. Not for diagnostic use or direct administration in to humans or animals.