The angiopoietins are a new family of growth factor ligands that bind to TIE2/TEK RTK (Receptor Tyrosine Kinase).
Browse angiogenesis pathways
Angiogenesis is the process by which new blood vessels are formed. It is important in growth and development as well as in wound healing, but it also plays a significant role in tumorigenesis. Several angiogenesis pathways include angiopoietin-TIE2 signaling and the VEGF family of ligands and receptor interactions.
Vascular endothelial growth factor (VEGF) is a highly-conserved genetic pathway that has evolved from simple to complex systems.
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