Wide Mouth Bottles

Nalgene wide mouth laboratory bottles are iconic, used in labs throughout the world. The wide mouth designs are easier to fill and are recommended for solid, semi-solid and viscous liquid materials. Those with mouth openings less than 100mm are guaranteed leakproof*. Choose from our rugged lab quality bottles, lower cost lighter weight economy bottles, and space-saving square and rectangular options. Thermo Scientific Nalgene bottles are made only from the highest quality plastic materials that meet pharmaceutical, laboratory and food grade standards; our plastic resins are selected to minimize additives and reduce potential leachables.   

Nalgene bottles are manufactured in our ISO 13485:2003 registered manufacturing facilities. Most of our plastic resin materials are DMF registered and meet a number of regulatory specifications including: USP Class VI, EP monographs, EU food-contact directives, CONEG, RoHS, CA Prop 65, SARA Title III Sec. 313, and 21 CFR pt 177. Nalgene containers are made from a wide variety of plastic types to meet the needs of virtually any laboratory application.  

For help selecting the Nalgene bottle that's perfect for your lab applications, use our online selection guide. For personal assistance, contact the   Nalgene Technical Support team.

Wide-Mouth Round PPCO
Lab Quality Bottle
 (2105-series) 
Wide-Mouth
Round LDPE 
Lab Quality Bottle (2103-series)
Wide-Mouth
Round HDPE 
Lab Quality Bottle (2104-series) 
Wide-Mouth Round Amber HDPE Lab Quality Bottle
(2106-series)
Large Wide-Mouth Round HDPE Bottle
(2120-series)

Large Wide-Mouth Round PPCO Bottle
(2120-series)

Traditional reusable lab bottle for long-term use and critical applications, autoclavable Traditional reusable lab bottle for long-term use and critical applications, squeezably flexible Traditional reusable lab bottle for long-term use and critical applications Amber color protects light-sensitive solutions. Traditional reusable lab bottle for long-term use and critical applications Larger size, rugged lab quality construction Larger size, rugged lab quality construction, Autoclavable
PPCO bottle
PP Closure
LDPE bottle
PP Closure
HDPE bottle
PP Closure
Amber HDPE bottle
amber PP closure
HDPE bottle
white PP Closure
PPCO bottle
white PP Closure
Milky white translucent Milky white translucent Milky white translucent Opaque amber bottle Milky white translucent Milky white translucent
30mL–1L 30mL–1L 30mL–1.5L 30mL–1L 2L–4L 2L–4L
Leakproof* Leakproof* Leakproof* Leakproof* Not liquid leakproof Not liquid leakproof
No graduations No graduations No graduations No graduations No graduations No graduations
Temp range
-40oC to 121oC
Temp range -100oC to 80oC Temp range -100oC to 120oC Temp range -100oC to 120oC Temp range -100oC to 120oC Temp range -40oC to 121oC
Autoclavable Not autoclavable Not autoclavable Not autoclavable Not autoclavable Autoclavable
Complies with Part 21 CFR 177.1520
for food use
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520 for food use
BPA-Free  BPA-Free  BPA-Free  BPA-Free  BPA-Free  BPA-Free 
Phthalate-free Phthalate-free Phthalate-free Phthalate-free Phthalate-free Phthalate-free
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
   

General chemical compatibility

  Wide-Mouth Round PPCO
Lab Quality Bottle
 (2105-series) 
Wide-Mouth 
Round LDPE 
Lab Quality Bottle
(2103-series)
Wide-Mouth 
Round HDPE 
Lab Quality Bottle
(2104-series) 
Wide-Mouth Round Amber HDPE Lab Quality Bottle 
(2106-series)
Large Wide-Mouth Round HDPE Bottle
(2120-series)

Large Wide-Mouth Round PPCO Bottle
(2120-series)
Acids, dilute
or weak
E E E E E E
Acids^ strong,
concentrated
G G G G G G
Alcohols, aliphatic E E E E E E
Aldehydes G G G G G G
Bases/alkali E E E E E E
Esters G G G G G G
Hydrocarbons, aliphatic G F G G G G
Hydrocarbons, aromatic  N N N N N N
Hydrocarbons, halogenated  N N N N N N
Ketones, aromatic N N N N N N
Oxidizing agents, strong F F F F F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20 o
 G  Little or no damage after 30 days constant exposure at 20oC
 F  Some effect after 7 days constant exposure at 20oC
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Wide-Mouth Round HDPE Economy Bottle
(2189-series)
Wide-Mouth Round HDPE Economy Bottle Bulk Pack (332189-series) Wide-Mouth Round HDPE Amber Economy Bottle (DS2185-series) Wide-Mouth Round PPCO Economy Bottle
(2187-series)
Lower cost, lighter weight, thinner wall for light-duty applications Bulk packed for additional cost savings, lighter weight, thinner wall for light-duty applications  Amber color protects light-sensitive solutions. Lower cost, lighter weight, thinner wall for light-duty applications Lower cost, lighter weight, thinner wall for light-duty applications, autoclavable
HDPE bottle
PP Closure
HDPE bottle
PP Closure
Amber HDPE bottle
amber PP closure
PPCO bottle
PP Closure
Milky white translucent Milky white translucent Opaque amber bottle Milky white translucent
30mL–1L 60mL–1L 30mL–1L 30mL–1L
Leakproof* Leakproof* Leakproof* Leakproof*
No graduations No graduations No graduations No graduations
Temp range
-100oC to 120oC
Temp range
-100oC to 120oC
Temp range
-100oC to 120oC
Temp range
-40oC to 121oC
Not autoclavable Not autoclavable Not autoclavable Autoclavable
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use
BPA-Free  BPA-Free  BPA-Free  BPA-Free 
Phthalate-free Phthalate-free Phthalate-free Phthalate-free
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
Also available 
bulk packed, unassembled
Also available 
bulk packed, unassembled

General chemical compatibility

  Wide-Mouth Round HDPE Economy Bottle 
(2189-series)
Wide-Mouth Round HDPE Economy Bottle Bulk Pack (332189-series) Wide-Mouth Round HDPE Amber Economy Bottle (DS2185-series) Wide-Mouth Round PPCO Economy Bottle 
(2187-series)
Acids, dilute or weak E E E E
Acids^ strong, concentrated G G G G
Alcohols, aliphatic E E E E
Aldehydes G G G G
Bases/alkali E E E E
Esters G G G G
Hydrocarbons, aliphatic G G G G
Hydrocarbons, aromatic  N N N N
Hydrocarbons, halogenated  N N N N
Ketones, aromatic N N N N
Oxidizing agents, strong F F F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20oC.
 G  Little or no damage after 30 days constant exposure at 20oC.
 F  Some effect after 7 days constant exposure at 20oC.
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Wide-Mouth Square
HDPE Bottles
(2114-series)
Wide-Mouth Square
PPCO Bottles
(2110-series)
Large Wide-Mouth
Square HDPE Bottles
(2123-series)
Large Wide-Mouth
Square Bottles
(2122-series)
Space-saving square shape, wide mouth Space-saving square shape, wide mouth, autoclavable Large capacity, molded hand grip Large capacity, molded hand grip, autoclavable
HDPE bottle
PP Closure
PPCO bottle
PP Closure
HDPE bottle
white PP closure
PPCO bottle
white PP Closure
Milky white translucent Milky white translucent Milky white translucent Milky white translucent
60mL–1L 60mL–1L 4L 4L
Leakproof* Leakproof* Not liquid
leakproof
Not liquid
leakproof
No graduations No graduations No graduations No graduations
Temp range
-100oC to 120oC
Temp range
-40oC to 121oC
Temp range
-100oC to 120oC
Temp range
-40oC to 121oC
Not autoclavable Autoclavable Not autoclavable Autoclavable
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use
BPA-Free  BPA-Free  BPA-Free  BPA-Free 
Phthalate-free Phthalate-free Phthalate-free Phthalate-free

General chemical compatibility

  Wide-Mouth Square HDPE Bottles
(2114-series)
Wide-Mouth Square PPCO Bottles
(2110-series)
Large Wide-Mouth Square HDPE Bottles (2123-series) Large Wide-Mouth Square Bottles
(2122-series)
Acids, dilute or weak E E E E
Acids^ strong, concentrated G G G G
Alcohols, aliphatic E E E E
Aldehydes G G G G
Bases/alkali E E E E
Esters G G G G
Hydrocarbons, aliphatic G G G G
Hydrocarbons, aromatic  N N N N
Hydrocarbons, halogenated  N N N N
Ketones, aromatic N N N N
Oxidizing agents, strong F F F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20oC.
 G  Little or no damage after 30 days constant exposure at 20oC.
 F  Some effect after 7 days constant exposure at 20oC.
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Select the Nalgene dilution bottle that works for you

Nalgene dilution bottles make 1/10 and 1/100 dilutions simple. Graduated at 90mL and 99mL, with plenty of head space for reagent additions after dilution, often eliminating the need to transfer diluted samples to another container for further process steps.

Polypropylene copolymer (PPCO) dilution bottles offer the best chemical resistance and will hold up to Tween exposure even at high temperatures.

Polysulfone (PSF) dilution bottles feature better clarity and easier liquid level viewing, with higher graduation accuracy (PSF ±1ml versus PPCO ±4mL). 

Wide-Mouth HDPE
Rectangular Bottles
(2007-series)
Wide-Mouth Amber HDPE
Rectangular Bottle
(2009-series)
Space-saving rectangular shape Amber color protects
light-sensitive solutions,
space-saving rectangular shape
HDPE bottle
PP Closure
Amber HDPE bottle
PP Closure
Milky white translucent Opaque amber
125mL–2L 125mL–2L
Leakproof* Leakproof*
No graduations No graduations
Temp range
-100oC to 120oC
Temp range
-100oC to 120oC
Not autoclavable Not autoclavable
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use1
BPA-Free  BPA-Free 
Phthalate-free Phthalate-free

General chemical compatibility

  Wide-Mouth HDPE 
Rectangular Bottles 
(2007-series)
Wide-Mouth Amber HDPE 
Rectangular Bottle 
(2009-series)
Acids, dilute or weak E E
Acids^ strong, concentrated G G
Alcohols, aliphatic E E
Aldehydes G G
Bases/alkali E E
Esters G G
Hydrocarbons, aliphatic G G
Hydrocarbons, aromatic  N N
Hydrocarbons, halogenated  N N
Ketones, aromatic N N
Oxidizing agents, strong F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20oC.
 G  Little or no damage after 30 days constant exposure at 20oC.
 F  Some effect after 7 days constant exposure at 20oC.
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Wide-Mouth Round PPCO
Lab Quality Bottle
 (2105-series) 
Wide-Mouth
Round LDPE 
Lab Quality Bottle (2103-series)
Wide-Mouth
Round HDPE 
Lab Quality Bottle (2104-series) 
Wide-Mouth Round Amber HDPE Lab Quality Bottle
(2106-series)
Large Wide-Mouth Round HDPE Bottle
(2120-series)

Large Wide-Mouth Round PPCO Bottle
(2120-series)

Traditional reusable lab bottle for long-term use and critical applications, autoclavable Traditional reusable lab bottle for long-term use and critical applications, squeezably flexible Traditional reusable lab bottle for long-term use and critical applications Amber color protects light-sensitive solutions. Traditional reusable lab bottle for long-term use and critical applications Larger size, rugged lab quality construction Larger size, rugged lab quality construction, Autoclavable
PPCO bottle
PP Closure
LDPE bottle
PP Closure
HDPE bottle
PP Closure
Amber HDPE bottle
amber PP closure
HDPE bottle
white PP Closure
PPCO bottle
white PP Closure
Milky white translucent Milky white translucent Milky white translucent Opaque amber bottle Milky white translucent Milky white translucent
30mL–1L 30mL–1L 30mL–1.5L 30mL–1L 2L–4L 2L–4L
Leakproof* Leakproof* Leakproof* Leakproof* Not liquid leakproof Not liquid leakproof
No graduations No graduations No graduations No graduations No graduations No graduations
Temp range
-40oC to 121oC
Temp range -100oC to 80oC Temp range -100oC to 120oC Temp range -100oC to 120oC Temp range -100oC to 120oC Temp range -40oC to 121oC
Autoclavable Not autoclavable Not autoclavable Not autoclavable Not autoclavable Autoclavable
Complies with Part 21 CFR 177.1520
for food use
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520
for food use1
Complies with Part 21 CFR 177.1520 for food use
BPA-Free  BPA-Free  BPA-Free  BPA-Free  BPA-Free  BPA-Free 
Phthalate-free Phthalate-free Phthalate-free Phthalate-free Phthalate-free Phthalate-free
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
   

General chemical compatibility

  Wide-Mouth Round PPCO
Lab Quality Bottle
 (2105-series) 
Wide-Mouth 
Round LDPE 
Lab Quality Bottle
(2103-series)
Wide-Mouth 
Round HDPE 
Lab Quality Bottle
(2104-series) 
Wide-Mouth Round Amber HDPE Lab Quality Bottle 
(2106-series)
Large Wide-Mouth Round HDPE Bottle
(2120-series)

Large Wide-Mouth Round PPCO Bottle
(2120-series)
Acids, dilute
or weak
E E E E E E
Acids^ strong,
concentrated
G G G G G G
Alcohols, aliphatic E E E E E E
Aldehydes G G G G G G
Bases/alkali E E E E E E
Esters G G G G G G
Hydrocarbons, aliphatic G F G G G G
Hydrocarbons, aromatic  N N N N N N
Hydrocarbons, halogenated  N N N N N N
Ketones, aromatic N N N N N N
Oxidizing agents, strong F F F F F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20 o
 G  Little or no damage after 30 days constant exposure at 20oC
 F  Some effect after 7 days constant exposure at 20oC
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Wide-Mouth Round HDPE Economy Bottle
(2189-series)
Wide-Mouth Round HDPE Economy Bottle Bulk Pack (332189-series) Wide-Mouth Round HDPE Amber Economy Bottle (DS2185-series) Wide-Mouth Round PPCO Economy Bottle
(2187-series)
Lower cost, lighter weight, thinner wall for light-duty applications Bulk packed for additional cost savings, lighter weight, thinner wall for light-duty applications  Amber color protects light-sensitive solutions. Lower cost, lighter weight, thinner wall for light-duty applications Lower cost, lighter weight, thinner wall for light-duty applications, autoclavable
HDPE bottle
PP Closure
HDPE bottle
PP Closure
Amber HDPE bottle
amber PP closure
PPCO bottle
PP Closure
Milky white translucent Milky white translucent Opaque amber bottle Milky white translucent
30mL–1L 60mL–1L 30mL–1L 30mL–1L
Leakproof* Leakproof* Leakproof* Leakproof*
No graduations No graduations No graduations No graduations
Temp range
-100oC to 120oC
Temp range
-100oC to 120oC
Temp range
-100oC to 120oC
Temp range
-40oC to 121oC
Not autoclavable Not autoclavable Not autoclavable Autoclavable
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use
BPA-Free  BPA-Free  BPA-Free  BPA-Free 
Phthalate-free Phthalate-free Phthalate-free Phthalate-free
Also available
bulk packed, unassembled
Also available
bulk packed, unassembled
Also available 
bulk packed, unassembled
Also available 
bulk packed, unassembled

General chemical compatibility

  Wide-Mouth Round HDPE Economy Bottle 
(2189-series)
Wide-Mouth Round HDPE Economy Bottle Bulk Pack (332189-series) Wide-Mouth Round HDPE Amber Economy Bottle (DS2185-series) Wide-Mouth Round PPCO Economy Bottle 
(2187-series)
Acids, dilute or weak E E E E
Acids^ strong, concentrated G G G G
Alcohols, aliphatic E E E E
Aldehydes G G G G
Bases/alkali E E E E
Esters G G G G
Hydrocarbons, aliphatic G G G G
Hydrocarbons, aromatic  N N N N
Hydrocarbons, halogenated  N N N N
Ketones, aromatic N N N N
Oxidizing agents, strong F F F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20oC.
 G  Little or no damage after 30 days constant exposure at 20oC.
 F  Some effect after 7 days constant exposure at 20oC.
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Wide-Mouth Square
HDPE Bottles
(2114-series)
Wide-Mouth Square
PPCO Bottles
(2110-series)
Large Wide-Mouth
Square HDPE Bottles
(2123-series)
Large Wide-Mouth
Square Bottles
(2122-series)
Space-saving square shape, wide mouth Space-saving square shape, wide mouth, autoclavable Large capacity, molded hand grip Large capacity, molded hand grip, autoclavable
HDPE bottle
PP Closure
PPCO bottle
PP Closure
HDPE bottle
white PP closure
PPCO bottle
white PP Closure
Milky white translucent Milky white translucent Milky white translucent Milky white translucent
60mL–1L 60mL–1L 4L 4L
Leakproof* Leakproof* Not liquid
leakproof
Not liquid
leakproof
No graduations No graduations No graduations No graduations
Temp range
-100oC to 120oC
Temp range
-40oC to 121oC
Temp range
-100oC to 120oC
Temp range
-40oC to 121oC
Not autoclavable Autoclavable Not autoclavable Autoclavable
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use
BPA-Free  BPA-Free  BPA-Free  BPA-Free 
Phthalate-free Phthalate-free Phthalate-free Phthalate-free

General chemical compatibility

  Wide-Mouth Square HDPE Bottles
(2114-series)
Wide-Mouth Square PPCO Bottles
(2110-series)
Large Wide-Mouth Square HDPE Bottles (2123-series) Large Wide-Mouth Square Bottles
(2122-series)
Acids, dilute or weak E E E E
Acids^ strong, concentrated G G G G
Alcohols, aliphatic E E E E
Aldehydes G G G G
Bases/alkali E E E E
Esters G G G G
Hydrocarbons, aliphatic G G G G
Hydrocarbons, aromatic  N N N N
Hydrocarbons, halogenated  N N N N
Ketones, aromatic N N N N
Oxidizing agents, strong F F F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20oC.
 G  Little or no damage after 30 days constant exposure at 20oC.
 F  Some effect after 7 days constant exposure at 20oC.
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Select the Nalgene dilution bottle that works for you

Nalgene dilution bottles make 1/10 and 1/100 dilutions simple. Graduated at 90mL and 99mL, with plenty of head space for reagent additions after dilution, often eliminating the need to transfer diluted samples to another container for further process steps.

Polypropylene copolymer (PPCO) dilution bottles offer the best chemical resistance and will hold up to Tween exposure even at high temperatures.

Polysulfone (PSF) dilution bottles feature better clarity and easier liquid level viewing, with higher graduation accuracy (PSF ±1ml versus PPCO ±4mL). 

Wide-Mouth HDPE
Rectangular Bottles
(2007-series)
Wide-Mouth Amber HDPE
Rectangular Bottle
(2009-series)
Space-saving rectangular shape Amber color protects
light-sensitive solutions,
space-saving rectangular shape
HDPE bottle
PP Closure
Amber HDPE bottle
PP Closure
Milky white translucent Opaque amber
125mL–2L 125mL–2L
Leakproof* Leakproof*
No graduations No graduations
Temp range
-100oC to 120oC
Temp range
-100oC to 120oC
Not autoclavable Not autoclavable
Complies with
Part 21 CFR 177.1520
for food use1
Complies with
Part 21 CFR 177.1520
for food use1
BPA-Free  BPA-Free 
Phthalate-free Phthalate-free

General chemical compatibility

  Wide-Mouth HDPE 
Rectangular Bottles 
(2007-series)
Wide-Mouth Amber HDPE 
Rectangular Bottle 
(2009-series)
Acids, dilute or weak E E
Acids^ strong, concentrated G G
Alcohols, aliphatic E E
Aldehydes G G
Bases/alkali E E
Esters G G
Hydrocarbons, aliphatic G G
Hydrocarbons, aromatic  N N
Hydrocarbons, halogenated  N N
Ketones, aromatic N N
Oxidizing agents, strong F F

For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.

 E  No damage after 30 days constant exposure at 20oC.
 G  Little or no damage after 30 days constant exposure at 20oC.
 F  Some effect after 7 days constant exposure at 20oC.
 N  Not recommended. Immediate damage may occur.

Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)

*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except oxidizing acids; for oxidizing acids, see "Oxidizing acids, strong"

Technical support

For assistance choosing products appropriate for your application, please speak with a Nalgene Technical Support Representative team by phone at +1.585.586.8800 or (1.800.625.4327 US toll free), or email your request to   technicalsupport@thermofisher.com.

In Austria, France, Germany, Ireland, Switzerland and the United Kingdom please contact technical support by phone at +800 1234 9696 (toll free) or +49.6184.90.6321, or email your request to   techsupport.labproducts.eu@thermofisher.com.

Regulatory support: For regulatory documentation of product or material claims, please contact Nalgene Regulatory Support at   RocRegSupport@thermofisher.com

Resources

Additional resources
  • Break the Glass Habit Brochure
  • Bottle and Carboy Selection Guide
  • Plastic Properties Reference Magnet
  • Plastic Labware Chemical Resistance Wall Poster

Request resources