A wide range of products—flexibility for your research

Invitrogen™ Surface-activated Dynabeads™ are available in different sizes, with a hydrophobic or hydrophilic nature, and with a variety of surface chemistries (see Table 1 below). To obtain the best possible results it is important to choose a size and surface of the Dynabeads suited for your application. The choice will depend on the nature of the ligand. In most applications several Dynabeads products can be used.

Antibodies or other ligands can be coupled onto the beads for affinity protein capture.
(Click to enlarge.)

Table 1. Choose the right surface-activated Dynabeads for your application.

Ligand Target Dynabeads Tosyl-
Dynabeads Amine Dynabeads Epoxy
Antibody Low MW antigen1 or peptide 
Protein or antibody
Protein complex

Organelles     2
Antibody Fragment Phage1 or antibody
Protein Phage or carbohydrate
Nucleic acid
Peptide Phage1 or antibody
Carbohydrate Antibody  
Low MV antigen Antibody
Nucleic acids, oligonucleotide, aptamer, PNA Nucleic acid binding proteins1 4  
DNA1, RNA1 or PCR amplicons1   4  
Enzyme Substrate or target for enzyme degradation
Organic chemistry derivatization, including introduction of new functional groups  

  Best product choice for listed ligand and target.
Alternative choice for listed ligand and target.
  Can be used for listed ligand and target.
1. Dynabeads pre-coupled with streptavidin may be the best product choice.
2. Dynabeads M-450 Epoxy.
3. Dynabeads M-450 Epoxy are recommended for isolation, stimulation, and expansion of cells.
4. Bifunctional crosslinkers may be introduced to immobilize oligonucleotides onto the surface of Dynabeads Amine.

Surface-activated Dynabeads product list