COVER STORY

TUNEL Vision—Detect DNA fragmentation with Click-iT® TUNEL assays

For a reliable and reproducible TUNEL imaging assay, it is vital not only that the modified nucleotide is an acceptable substrate for TdT, but also that the detection method is sensitive and avoids any additional loss of cells from the sample. The Click-iT® TUNEL Imaging Assays meet both of these criteria.

New Technologies

Assess hERG channel blocks without radioactivity—The Predictor™ hERG Fluorescence Polarization Assay Kit

Characterization of type II kinase inhibitors and nonactivated kinases—The LanthaScreen® Eu Kinase Binding Assay

High-throughput chloride channel screening—Introducting the newest member of the Premo™ family: Premo™ Halide Sensor

Fluorescence technologies for high-content imaging and analysis—Cell health and toxicity assays

Novel solid-phase antibody labeling—Take advantage of the speed, efficiency, and convenience of APEX Antibody Labeling Kits

Automated cell counting at your fingertips—The Countess™ Automated Cell Counter

Practical Applications

Dynamic signaling by integrins—Protein phosphorylation and activation of networks

Targeting cardiovascular disease and Alzheimer's disease—Beyond regulating cholesterol levels, new drug targets emerge from lipid research

Modeling mammary cell function in three dimensions—BacMam-medicated transduction and 3D culture of primary mammary cells

Hassle-free western blots—WesternDot™ 625 Western Blot Kits

Departments

Journal Highlight—Staining DNA without altering its structure

On the Web—Easy access to Molecular Probes® products

Just Released—Highlighting our newest cellular analysis products and technologies

Endnote—Recently published: A look at how your fellow researchers are using our products