Low molecular weight, non-polar organic compounds in food contact materials are typically volatile and have the highest probability to migrate from or through polymeric contact material. Testing of the contact material is typically conducted by headspace sampling followed by gas chromatography and mass spectrometry (GC-MS).

Headspace GC-MS is a popular analytical technique and has been widely used in food packaging studies as it provides analytical advantages of chromatographic resolution, reproducibility, peak capacity and, importantly, extensive spectral libraries to aid in identification. Gas chromatography high resolution mass spectrometry (GC-HRMS) is becoming increasingly popular, enabling the identification and quantification of unknown compounds.

Volatile Analysis for Food Packaging Materials workflow

Volatiles are released from materials using headspace sampling. USP methods suggest the use of valve-and-loop headspace sampling systems. Ultraclean Thermo Scientific™ Chromacol™ headspace vials help ensure low background and leak free seals.

Modular GC allows your choice of injectors, together with helium saver options and the widest range of advanced column technologies, including Thermo Scientific™ TraceGOLD™ GC column phases for volatiles.

Sensitive mass spectrometry delivers both quantitation and qualification of volatiles. Thermo Scientific™ ISQ™ Series Quadrupole GC-MS features a new source design ideal for continuous high-throughput operation.

Simple to operate and fully compliant Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System (CDS) software provides mass spectrometry data acquisition and processing for GxP environments.


Featured resources

To accurately determine presence of chemical migrants from paperboard packaging to food products using solid phase microextraction (SPME) followed by gas chromatography-triple quadrupole mass spectrometry.

Headspace analysis by means of a dedicated autosampler is a standard technique for the determination of volatile organic compounds (VOCs) possibly present in food packaging materials.

To prevent excessive amounts of residual solvents (VOCs) in the final packaging of material products, whose presence would seriously compromise their quality, an efficient online control over the whole process is required.

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