Cyclophilin B is a member of the B subfamily of the cyclophilin family of peptidylprolyl isomerases. It is found in the endoplasmic reticulum and is secreted in biological fluids. Within the cell, cyclophilin B acts as a chaperone for molecules meant for secretion by stabilizing the molecules and facilitating other chaperone molecules. When secreted, cyclophilin B is involved in T cell adhesion to fibronectin and in chemotaxis.

Cyclophilin B is conserved, ubiquitous, and abundantly expressed in most cells, making it a good loading control. Quality Invitrogen cyclophilin B antibodies are available for a variety of research needs.

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Immunohistochemical analysis of cyclophilin B in paraffin-embedded hepatoma. A cyclophilin B polyclonal antibody (Cat. No. PA5-31172) was used at a dilution of 1:500.