Membrane Filter

Whether you're filtering for analytical, clarification or sterilization purposes, our membranes are specifically selected to support your filtration needs. However, identifying which filter material to use based on the properties of the fluid or gas type is absolutely critical to achieve peak filtration performance. 

  • If you're most interested in the fluid coming through the membrane filter, or the filtrate, membranes that are lower in extractables and have high flow rates would best fit your needs. 
  • If you're analyzing what is left behind on the membrane, or the retentate, membranes with a smooth surface and proper structure will be most fitting for analytical usage.

In both applications, the nature of your fluid will also play a role in your selection, as membranes with very high binding of proteins, peptides and nucleic acids may clog prematurely, removing desired materials from the filtrate or obscuring what you want to discover in the retentate. If you are not sure what filter material to choose, our technical support team, equipped with a full analytical testing lab, can help you through the process. 

Membrane abbreviations

   
  • SFCA: Surfactant-free cellulose acetate
  • aPES: Asymmetrical polyethersulfone
  • PTFE: Polytetraflouroethylene
  • NYL: Nylon
  • CN: Cellulose nitrate
  • CA: Cellulose acetate
  • GF: Glass fiber

Application properties

 

SFCA

aPES

PTFE

NYL

CN

CA

GF

Cell culture        
Sera        
Molecular biology solutions        
Water        
Buffers        
Salt solutions            
Solvent filtration            
Gas filtration            
Venting            
Ameno acid solutions            
Prefiltration            
Serial filtration            

Material properties

 

SFCA

aPES

PTFE

NYL

CN

CA

GF

Hydrophilic    
Hydrophobic      
Autoclave
Flow rate Medium
to high
High High to 
very high
Low to 
medium
High High Very high
Throughput Medium High High Low Medium Medium Very high
Extractables Low Low Very low Very low Medium Medium Low
Protein binding  Low Low Very low High High Low Medium

Hydrophobic


Chemical compatibility

 

SFCA

aPES

PTFE

NYL

CN

CA

GF

Acids M S2 M U S M S2
Bases (Caustics) M S2 U S S M S2
Alcohols S S M S S S S
Ketones U U U S S U S
Esters U M U M S U S
Ethers U U U S S U S
Oxidizers U U M U S U S
Aldehydes U M M S S U S
Aliphatic hydrocarbons S M S S S S S
Aromatic hydrocarbons S S S S S S S
Halogenated hydrocarbons M M S S S M S
 S  Satisfactory resistance
 S2  Satisfactory below 26°C only
 M  Marginal resistance; may be satisfactory for short-term exposure
 U  Unsatisfactory resistance; may cause failure and/or dissolve the membrane.

Featured videos

View the Nalgene rapid-flow advantage
 

Cell culture contamination and using filtration as a final preventative measure