More clinical biomarkers. More accurately. Faster than ever.

More clinical biomarkers. More accurately. Faster than ever.

A major challenge of clinical &  translational research is to discover potential, clinically relevant biomarkers in a reliable way. Then, moving beyond positive identification discovery to verification and validation in the shortest possible time. Mass spectrometry potentially enables new screening and clinically relevant tests and supports developing targeted therapeutics. Bridging the gap from discovery to verification and validation requires high-performing instruments and software, as well as high-level competence in MS-based biomarker discovery and in method development for biomarker verification.

Unless otherwise noted, all products are for research use only, not for use in diagnostic procedures.

Featured mass spectrometry instruments

Mass Spectrometry Instruments

Childrens Hospital Boston
Bringing Mass Spectrometry into Your Laboratory

Critical Consideration for Success

Mark Kellogg, PhD, DABCC, Associate Director of Chemistry at Boston Children’s Hospital discusses his road to bringing mass spectrometry in his laboratory and what you need to know adequately prepare.

Watch this webinar ›

  • Combines a high-capacity transfer tube allows for maximum ion loading, an electrodynamic ion funnel that accomodates and transmits ions over a broader mass range, and a high-field Orbitrap mass analyzer.
  • Enables fast identification and analysis of peptides, label-free and TMT quantitation, top-down proteomics analyses, sophisticated DDA and DIA, dynamic Retention Time PRM and BioPharma characterization.
  • Superb sensitivity that generates data for all molecular species, even in complex matrices.
  • Outstanding robustness enables increased confidence in data while prolonging instrument uptime.
  • Reliability and reproducibility improve data quality for every run and every sample.

Ideal for protein identification, intact protein analysis, shotgun lipidomics, metabolomics, and high-throughput proteomic and screening workflows, targeted quantification and unknown retrospective identification

  • Orbitrap Analyzer
  • Mass Range m/z 50-6000
  • Mass Accuracy < 1ppm
  • Mass resolution up to  280,000 with option Extended Mass Range (EMR)
  • Scan speed up to 12Hz MS and MS/MS
  • Protein Mode
  • Wide dynamic range and ultrahigh mass resolution allow identification of more low-abundance proteins with confidence.
  • Tribrid architecture provides unprecedented depth of analysis and ease of use.
  • Innovative software and instrument design lets you concentrate on your science.

Offers the quantitative power of a GC triple quadrupole MS combined with high-precision, full scan HR/AM capabilities.  

  • Mass range: 50 to 3,000 m/z
  • Detection limit <6 fg OFN
  • Quantitative dynamic range: > 106 
  • Resolving power up to 100,000 at m/z 272
  • Part-per-trillion-level sensitivity

Designed for and developed with high throughput analytical labs to deliver the highest productivity, with MS/MS simplicity and even higher performance SRM.

  • Mass range: 1.2 to 1100 u
  • Detection limit ≤ 0.4 fg OFN depending on configuration
  • Scan up to 20,000 u/s
  • Up to 800 SRM transitions

Whether you perform routine total elemental analyses or state of the art research, this unique system delivers powerful, highly sensitive trace detection, fast. With three models available, the iCAP RQ ICP-MS is the ideal tool for a wide range of applications and market sectors, from routine 24/7 analysis to demanding high quality research.

Increase sample throughput in your laboratory with Thermo Scientific CETAC Autosamplers.

  • CETAC ASX-260 Autosampler offers a 180 sample capacity for low-moderate sample throughput
  • CETAC ASX-520 Autosampler accommodates up to 360 samples for moderate-high sample throughput
  • Combines a high-capacity transfer tube allows for maximum ion loading, an electrodynamic ion funnel that accomodates and transmits ions over a broader mass range, and a high-field Orbitrap mass analyzer.
  • Enables fast identification and analysis of peptides, label-free and TMT quantitation, top-down proteomics analyses, sophisticated DDA and DIA, dynamic Retention Time PRM and BioPharma characterization.
  • Superb sensitivity that generates data for all molecular species, even in complex matrices.
  • Outstanding robustness enables increased confidence in data while prolonging instrument uptime.
  • Reliability and reproducibility improve data quality for every run and every sample.

Ideal for protein identification, intact protein analysis, shotgun lipidomics, metabolomics, and high-throughput proteomic and screening workflows, targeted quantification and unknown retrospective identification

  • Orbitrap Analyzer
  • Mass Range m/z 50-6000
  • Mass Accuracy < 1ppm
  • Mass resolution up to  280,000 with option Extended Mass Range (EMR)
  • Scan speed up to 12Hz MS and MS/MS
  • Protein Mode
  • Wide dynamic range and ultrahigh mass resolution allow identification of more low-abundance proteins with confidence.
  • Tribrid architecture provides unprecedented depth of analysis and ease of use.
  • Innovative software and instrument design lets you concentrate on your science.

Offers the quantitative power of a GC triple quadrupole MS combined with high-precision, full scan HR/AM capabilities.  

  • Mass range: 50 to 3,000 m/z
  • Detection limit <6 fg OFN
  • Quantitative dynamic range: > 106 
  • Resolving power up to 100,000 at m/z 272
  • Part-per-trillion-level sensitivity

Designed for and developed with high throughput analytical labs to deliver the highest productivity, with MS/MS simplicity and even higher performance SRM.

  • Mass range: 1.2 to 1100 u
  • Detection limit ≤ 0.4 fg OFN depending on configuration
  • Scan up to 20,000 u/s
  • Up to 800 SRM transitions

Whether you perform routine total elemental analyses or state of the art research, this unique system delivers powerful, highly sensitive trace detection, fast. With three models available, the iCAP RQ ICP-MS is the ideal tool for a wide range of applications and market sectors, from routine 24/7 analysis to demanding high quality research.

Increase sample throughput in your laboratory with Thermo Scientific CETAC Autosamplers.

  • CETAC ASX-260 Autosampler offers a 180 sample capacity for low-moderate sample throughput
  • CETAC ASX-520 Autosampler accommodates up to 360 samples for moderate-high sample throughput
Resources

Technical notes