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Learn how CaptureSelect can enable the purification of correctly post translationally modified recombinant proteins: a custom case study

Thermo Fisher Scientific has collaborated with MedImmune to develop two custom affinity resins based on VHH antibody fragments, targeting recombinant proteins with the most desired specificity. The first resin was able to selectively bind to the amidated, more active form of the protein, while the second resin was able to distinguish the most active substance from a mixture of post-translationally modified variants.

Download this publication from Biotechnology Journal today to learn more about custom affinity chromatography development using camelid VHH antibody fragments, and their potential to purify highly pure and active biological therapeutics.

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