One of the most significant standards introduced by the USP has been to set limits for the four elemental contaminants in dietary supplements: arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg). The new limits are summarized in the USP-NF General Chapter <2232> which replaces Chapter <231>, a hundred-year old heavy metals colorimetric test based on metal sulfide precipitation which is visually compared to a lead standard.
Download the white paper to better understand the new methodology described in United States Pharmacopeia (USP) Chapter <2232>, which sets limits for elemental contaminants in dietary supplements. Learn additional guidance on the best technique to use for this application and how to optimize the analytical procedures in order to meet the requirements of the regulatory agencies involved.
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