Metabolite Detection, Quantitation and Characterization – Comprehensive and confident metabolomics analysis

Comprehensive and confident metabolomics analysis

Leading Orbitrap-based mass spectrometers provide the high-resolution, accurate-mass (HRAM) measurements and sensitivity for highly reproducible untargeted and targeted analysis of metabolomics and lipidomics samples. Fast data acquisition and polarity switching maximize productivity by detecting both positive and negative ions in a single analysis. For routine and well characterized metabolites, the TSQ series of triple quadrupole MS systems provides unrivaled flexibility and sensitivity for SRM-based targeted quantitation of metabolites.

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Featured metabolite detection, quantitation and characterization categories

Combined with high resolution IC or LC separations, the Thermo Scientific Q Exactive HF MS system provides the reproducibility, high sensitivity and wide dynamic range for comprehensive untargeted and targeted metabolomics research.

Designed for GC separations, the Thermo Scientific Q Exactive GC Orbitrap GC-MS/MS system provides highly accurate data for quantification of all detectable compounds with high specificity and selectivity. The system has a wide dynamic range and excellent resolution for the simultaneous quantitation and confirmation of both high- and low-abundance metabolites.

The proven power of Orbitrap technology and rich MSn spectra from multiple fragmentation techniques come together in the Thermo Scientific Orbitrap Fusion Lumos Tribrid mass spectrometer. This system's combination of ultra-high resolution, high mass accuracy, wide dynamic range, and high sensitivity offer no compromise in terms of structural elucidation/identification.

For routine well characterized metabolites, the Thermo Scientific TSQ Altis triple quadrupole mass spectrometer exceeds even the most stringent analytical requirements with superb sensitivity, speed and dynamic range for SRM-based targeted metabolomics applications.

For routine well characterized metabolites amenable to GC separations, the Thermo Scientific TSQ 9000 triple quadrupole GC-MS/MS delivers the highest productivity with superb sensitivity, speed, and dynamic range for SRM-based quantitation of targeted metabolomics applications.