Thermo Scientific DHX heat exchanger

DHX Heat Exchanger

Our innovative modular system uses single-use BioProcess Containers (BPCs) as the sterile fluid path. The BPCs fit tightly between five stainless steel plates, efficiently transferring heat in a counter-current flow path.

The sterile, single-use fluid path makes the system an ideal choice for heat transfer during fermentation, collection of harvest media and protein processing. The DHX Heat Exchanger provides efficient, sterile heat transfer that easily integrates into any process


Benefits of the DHX Heat Exchanger

Key features and benefits

  • Completely isolated flow paths for process fluid and heat transfer fluid
  • Countercurrent, serpentine flow patterns
  • Dimpled jacketing on the plates provides turbulent flow
  • BPCs fill in place with no operator interaction
  • Modular design and small footprint allows for changing process needs
  • Reduced infrastructure requirements and processing time
  • Improved product consistency

Applications

  • Media hold
  • Mixing and fermentation
  • Cell separation/protein harvest
  • Harvest cooling
  • Buffers
  • Protein purification
  • Bulk drug substance

Countercurrent flow between the heating/cooling fluid and the process fluid

The purple shading depicts the serpentine flow path of the process fluid in the bags. The dimpled plate behind the single-use bag depicts where the heating/cooling fluid flows in a countercurrent fashion to the process fluid in a completely isolated flow path.

 

Key features and benefits

  • Completely isolated flow paths for process fluid and heat transfer fluid
  • Countercurrent, serpentine flow patterns
  • Dimpled jacketing on the plates provides turbulent flow
  • BPCs fill in place with no operator interaction
  • Modular design and small footprint allows for changing process needs
  • Reduced infrastructure requirements and processing time
  • Improved product consistency

Applications

  • Media hold
  • Mixing and fermentation
  • Cell separation/protein harvest
  • Harvest cooling
  • Buffers
  • Protein purification
  • Bulk drug substance

Countercurrent flow between the heating/cooling fluid and the process fluid

The purple shading depicts the serpentine flow path of the process fluid in the bags. The dimpled plate behind the single-use bag depicts where the heating/cooling fluid flows in a countercurrent fashion to the process fluid in a completely isolated flow path.

 

DHX Heat Exchanger overview video

Sterile, efficient, and modular

Learn how the DHX Heat Exchanger provides efficient, sterile heat transfer that easily integrates into any new and existing process.


Ordering information