Design and Order RNAi Reagents
Select from among eight tools to locate off-the-shelf reagents or design your RNAi reagents for a particular gene target.
siRNA for Cell Culture
|siRNA Type||Description||Design Now|
|Silencer® Select siRNA||Silencer® Select siRNAs are the next generation of Ambion® siRNAs. These siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications to yield siRNAs with excellent efficacy, potency, and specificity.||order|
|Stealth RNAi™ siRNA||Stealth RNAi™ siRNA improves upon these traditional duplexes by using proprietary chemical modifications to help ensure better RNAi results. Stealth RNAi™ siRNA uses next-generation RNAi chemistry that allows for higher specificity and increased stability in serum and cell culture compared to standard siRNA.||order|
|Unmodified Alexa Fluor® dye–labeled siRNA||Traditional unmodified siRNA duplexes synthesized on demand with the highest quality BLOCK-iT™ siRNAs.||order|
|Unmodified/unlabeled siRNA||Traditional unmodified siRNA duplexes synthesized on demand with the highest quality Silencer® siRNAs.||order|
RNA interference (RNAi) is the best way to effectively knock down gene expression to study protein function in a wide range of cell types. Traditional RNAi methods for gene knockdown in mammalian cells involved the use of synthetic RNA duplexes consisting of two unmodified 21-mer oligonucleotides annealed together to form short/small interfering RNAs (siRNAs). Stealth RNAi™ siRNA and Silencer® Select siRNA improve upon these traditional duplexes by using proprietary chemical modifications to help ensure better RNAi results.
For Research Use Only. Not intended for animal or human therapeutic or diagnostic use.