Ion Newsletter—Issue 24
2018, Issue 24
New: Ion GeneStudio S5 Series for next-generation sequencing
Meet our expanded NGS instrument lineup: Ion GeneStudio S5 System, Ion GeneStudio S5 Plus System and Ion GeneStudio S5 Prime System.
Ion GeneStudio S5 sequencers can meet the research needs of the occasional NGS user, up to central service laboratories that need to sequence a broad range of sample types and applications and return the data very quickly.
New: Ion 550 Chip reducing cost per sample
Sequence up to 8 exomes in a working day and reduce your cost per sample up to 40% sequencing exomes, transcriptomes, or larger gene panels.
Target >50 genes across multiple cancer types in research
Ion Torrent Oncomine Pan-Cancer Cell-Free Assay enables reproducible detection and analysis of tumor DNA and RNA across all major classes of somatic mutations (SNVs, indels, CNVs and fusions) from a single vial of blood and from as little as 1 ng of nucleic acid input within two days.
Targeting over 50 genes across multiple cancer types, including lung, colorectal, breast, pancreatic, thyroid and others, the cell-free total nucleic acid (cfTNA) assay is the latest addition to the rapidly growing liquid biopsy NGS assay portfolio.
Inherited disease research made easy with over 5,000 pre-tested genes
Over 5,000 genes related to germline disorder research are now available in the Ion AmpliSeq On-Demand catalog. Log on to Ion AmpliSeq Designer to check the availability of your genes. Custom gene panels are now more accessible than ever with easy gene selection and small pack sizes.
One single assay for relevant myeloid mutations
Current methods for the analysis of hematological malignancies often involve multiple sequential tests and laborious workflows.
The Ion Torrent Oncomine Myeloid Research Assay is a comprehensive, targeted NGS assay designed to assist in the understanding of myeloid cancer. The assay interrogates relevant DNA mutations and fusion transcripts associated with myeloid disorders in a quick and easy NGS run.
Immuno-oncology promises deeper research understanding
The Ion Torrent immuno-sequencing solution, now with Onomine Tumor Mutation Load, is designed to help identify markers relevant to immunotherapies using our streamlined sequencing platform and fully integrated informatics solutions to analyze and interpret results.
Need to store your data?
New advancement in library prep coming soon
Later this year, a new advancement in library preparation, Ion AmpliSeq HD technology*, will be ideal for ultralow frequency variant detection from both liquid biopsy and FFPE samples. Its primer design process will enable clinical researchers to, for the first time, create cell-free DNA (cfDNA) panels of their own design with maximum flexibility.
*The content provided herein may relate to products that have not been officially released and is subject to change without notice.
Learn how next-generation sequencing can be used in your research
Bite-sized answers to your sequencing questions for next-generation sequencing or capillary electrophoresis
Detecting TCR beta variable gene alleles
The immune response workflow in Ion Reporter now has a plug-in that is an accessory to the Ion AmpliSeq Immune Repertoire Assay Plus, TCR beta, which helps users detect TCR beta variable gene alleles. The plug-in produces report files containing the sequence and frequency of putative novel alleles and also crosschecks putative novel alleles with the Lym1K database (Yu et al, 2017) derived from 1,000 genomes data.
** No purchase necessary. Participation is limited to researchers and purchasing personnel working in the life sciences industry who are 21 years of age or older who submit a completed submission form. Offer valid on requests received by Life Technologies no later than December 15, 2018. Limit to one Connect account free per participant. The estimated value of 100 GB of storage is $24 per year. Offer void where prohibited by federal, state, provincial, or local laws or regulation or agency/institutional policy. Other restrictions may apply.
For Research Use Only. Not for use in diagnostic procedures.