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Tumors can be broadly divided into two classes: those that are driven by mutations (M class), and those that are driven by copy number changes (C class). Therefore, you could be missing the real cancer drivers by only looking at somatic mutations.

Obtaining reliable whole-genome copy number data from degraded FFPE samples can be challenging with traditional methodologies. OncoScan™ FFPE Assay Kit, powered by molecular inversion probe (MIP) technology, enables detection of large and small copy number variations and copy-neutral loss of heterozygosity (LOH) in FFPE, generating data from 80 ng of DNA sample in 48 hours.

“C class” and “M class” tumors

What do we mean when talking about C class and M class tumors? Which tumors belong to which class? Learn more in this Nature Genetics paper.
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Scientist Spotlight

Gordon Mills, MD, PhD at MD Anderson Cancer Center believes that research on C class tumors holds potential for improved cancer therapy.
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Identifying genomic biomarkers

See how OncoScan FFPE Assay Kit helped Dr. Joshua Schiffman discover novel biomarkers in pediatric cancer.
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